| abstract |
A method for producing a microfoam of a physiologically acceptable gas dispersible in the blood capable of dissolving substantially completely in or being absorbed by the blood and an aqueous sclerosing liquid suitable for use in sclerotherapy of blood vessels, characterized in that it comprises passing a mixture of a physiologically acceptable gas dispersible in the blood and an aqueous sclerosing liquid through passages having at least a cross-sectional dimension comprised between 0.1 and 30 pm provided as multiple openings in one or more elements located along the flow and comprising a perforated sheet or membrane, a mesh, a sieve or a sintered material, the gas-to-liquid ratio being controlled such that, during the flow through the passages, a microfoam is produced having a density comprised between 0.07 g / ml and 0.19 g / ml, having a half-life of at least 2 minutes. |