http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2254028-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa5b188f2c01cc60c10fa482edd2f4ec |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-48 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-013 |
filingDate | 2004-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2007-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed089bc823eef0a8e41b2361cce55570 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b32e08daa868d5333d22dd8a65cc1704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81c4b08b3026da4afa13a010a5ce182b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4091ea0fe5620da8f907417c3ef69ed5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2098d18eb0c8d81a1c42aaf4829da87 |
publicationDate | 2007-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2254028-B1 |
titleOfInvention | PROCEDURE FOR OBTAINING PRAVASTATIN SODIUM PURIFIED. |
abstract | Procedure for obtaining pravastatinnpurified sodiumn n n Simple, fast, economical andneasy industrial scaling, to obtain pravastatin sodiumnpurified from a fermentation broth, which comprises thenformation of an enriched aqueous solution of pravastatin, thenobtaining and isolation of pravastatin sodium or rawnpravastatin calcium and conversion to pravastatin sodiumnpurified by suspension in water, adjust to acidic pH,nextraction with organic solvent such as ethyl acetate or methylnisobutyl ketone, adding a solution of acid sodium saltncarboxylic acid in low molecular weight alcohol, such as octanoatensodium in methanol and isolation of purified sodium pravastatinnby filtration, allowing to obtain a quality final productnpharmaceutical optionally applying a recrystallization processnto the purified pravastatin sodium obtained. |
priorityDate | 2004-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.