http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2250000-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65f6765a6f0387cfcb75bc6a09213161 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
filingDate | 2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2007-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d00b0048af9da5a9121809823d9bf586 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39ad393f4514a34090f92d20288354c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a37fd34722cd332f7196293f4ab2ec8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c16de8b94237a5a4bd9ff09dafaff77c |
publicationDate | 2007-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2250000-B1 |
titleOfInvention | PROCEDURE FOR PREPARATION OF ZIPRASIDONE. |
abstract | Procedure for the preparation ofnziprasidone The present invention relates to a process for thenpreparation ofn5- (2- (4- (1,2-benzisothiazol-3-yl) -1-piperazinyl) ethyl) -6-chloro-1,3-dihydro-2H-indole-2-onenof formula I, or of a pharmaceutically acid addition saltnacceptable, solvate, hydrate or clathrate thereof, which comprisesnreacting a compound of formula II in which X is an atomnhalogen, with a compound of formula III, which may be saidncompound of formula III in the form of a free base or a salt ofnaddition with an organic or inorganic acid, characterized in thatnsaid compounds of formula II and III are reacted innpresence of a neutralizing agent, and of a solvent thatnunderstand acetonitrile. |
priorityDate | 2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.