http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2248622-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34bd4e87ecbca17f16d460ca394e60f9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 |
| filingDate | 2002-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f1cee1e0f19d67c5fe906c48a866dd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6889028b6c4efe924d918c8bd0196b4c |
| publicationDate | 2006-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2248622-T3 |
| titleOfInvention | MEDICINAL PRODUCT CONTAINING 3- (3-DIMETHYLAMINE-1-ETIL-2-METHYLPROPIL) PHENOL AND PROVIDING A DELAYED RELEASE OF THE ACTIVE PRINCIPLE. |
| abstract | Delayed-release pharmaceutical formulation containing 3- (3-dimethylamino-1-ethyl-2-methylpropyl) phenol or a pharmaceutically acceptable salt thereof in a delayed-release matrix of the active substance, where the matrix contains 1 to 80% in weight of one or more hydrophilic or hydrophobic polymers as a pharmaceutically acceptable matrix former and has the following release rate in vitro, measured by the method of Ph. Eur. Paddle at 75 rpm in a buffer (according to Ph. Eur.) with a pH of 6, 8 at 37 ° C and with UV spectrometric detection: 3-35% by weight (based on 100% by weight of the active substance) of 3- (3-dimethylamino- 1-ethyl-2-methylpropyl) phenol released after 0.5 hours, 5-50% by weight of 3- (3-dimethylamino-1-ethyl-2-methylpropyl) phenol released after 1 hour, 10-75% by weight of 3- (3-dimethylamino-1-ethyl-2-methylpropyl) phenol released after 2 hours, 15-82% by weight of 3- (3-dimethylamino-1-ethyl-2-methylpropyl) phenol released after 3 hours, 30-97% by weight of 3- (3-dimethylamino-1-ethyl-2-methylpropyl) phenol released after 6 hours, more than 50% by weight of 3- (3-dimethylamino-1-ethyl -2-methylpropyl) phenol released after 12 hours, more than 70% by weight of 3- (3-dimethylamino-1-ethyl-2-methylpropyl) phenol released after 18 hours, more than 80% by weight 3- (3-Dimethylamino-1-ethyl-2-methylpropyl) phenol released after 24 hours. |
| priorityDate | 2001-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.