| abstract |
A tricyclic derivative of pyrrole or pyrazole represented by the following general formula (I), or a pharmaceutically acceptable salt thereof, which shows great affinity and selectivity for the 5-HT {sub, 2C} receptor and is useful for the treatment of Central nervous system diseases such as sexual disorders, appetite disorders, anxiety, depression and sleep disorders. * formula * (in the formula above, each symbol represents the following; Ring Y: an unsaturated ring of five elements that can have 1 to 3 of one or more types of heteroatom (s) each selected from the group consisting of an atom of nitrogen; an oxygen atom and a sulfur atom or a six-membered unsaturated ring having 1 or 2 nitrogen atom (s); X: a bond or a carbon atom; .... a double bond or a single bond; V: a nitrogen atom or a group represented by a formula CH, and A: a linear or branched lower alkylene group that can be substituted by a halogen atom or a cycloalkyl group). |