| abstract |
Compounds of the ** formula **, in which they mean R1, R2, independently of one another, NR6R7, piperidine, piperazine, tetrahydropyridine, the rings being able to be substituted in each case with phenyl, (C1-C6) alkyl-phenyl, (C1-C8) alkyl, (CO) -C1-C6 alkyl; R6 and R7, independently of each other, H, (C1-C6) alkyl, (C1-C6) alkyl -NH-C1-C6 alkyl, (C1-C6) alkyl -N- [(C1-C6) alkyl ] 2, (CH2) n-Ar, where n can be = 0-6 and Ar can be equal to phenyl, 2-, 3- or 4-pyridyl, piperidinyl, pyrrolidinyl, 2-, 4- or 5-pyrimidinyl, 2 -pyrazinyl, 2-, 3- or 4- morpholinyl, and Ar may be substituted up to twice with F, Cl, Br, OH, CF3, NO2, CN, OCF3, O-C1-C6 alkyl, (C1-alkyl) -C6), COOH, NH2, (CH2) -phenyl, where n = 0-3; X (C1-C6) alkyl, (CH2) -phenyl, where n can be = 0-6; and the phenyl radical may be substituted, up to twice, with F, Cl, Br, CF3, CN, OCF3, O-C1-C6 alkyl, S-C1-C6 alkyl, C1-C8 alkyl, cycloalkyl (C3-C6), COOalkyl (C1-C8), COOcycloalkyl (C3-C6), CONH2, CONHalkyl (C1-C8), CON [(C1-C6) alkyl] 2; R3 NR10R11, piperazine; R10, R11, independently of each other, H, (C1-C6) alkyl, (C3-C6) cycloalkyl, CO (C1-C6) alkyl, (C1-C6) alkyl -CO-(C1-C6) alkyl, SO2-benzyl-OCH3, (CH2) n-Ar, where n can be = 0-6 and Ar can be equal to phenyl or thienyl; as well as its physiologically compatible salts. |