http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2245604-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e19ed5092514d4f22acfa3bc98b8b572 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-16 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-40 |
filingDate | 2004-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09210d17e3591de3019e2e7af7052a14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b5a42341f0fdcff0b603c4e685c002b |
publicationDate | 2006-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2245604-A1 |
titleOfInvention | PROCEDURE FOR OBTAINING 2-AMINO-6-ALQUIL-AMINO-4,5,6,7-TETRAHYDROBENZOTIAZOLES. |
abstract | Procedure for obtainingn2-amino-6-alkyl-amino-4,5,6,7-tetrahydrobenzothiazoles.n n n The procedure for the preparation ofn2-amino-6-alkyl-amino-4,5,6,7-tetrahydrobenzo-thiazolesn(I) where the asterisk (*) represents an asymmetric carbon and R1 isnC1-C6 alkyl; their enantiomers or mixtures ofnthemselves, their solvates, hydrates or acceptable saltsnPharmaceutically, it comprises: (a) reacting a compound (II)nwith a secondary amine, optionally in the presence of an acid andna solvent 1, to form an enamine; (b) optionally withdrawnsaid acid and said solvent 1, and then donreacting said enamine with sulfur in the presence of a solventn2; and (c) reacting the previously obtained compound withncyanamide to obtain the compound (I). Among the compounds (I)nis pramipexole, a compound with agonist activitynD-2 dopamine, useful for the treatment ofnParkinson's disease and schizophrenia. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8952173-B2 |
priorityDate | 2004-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.