| abstract |
Losartan derivatives with propertiesnantioxidantsn n n The creation of drugs with propertiesnAngiotensin II receptor blockers and simultaneouslynantioxidants, may be beneficial to prevent damagenTissue in patients with cardiovascular risk. At the momentninvention describes the preparation of esters of Losartan, anAngiotensin II antagonist well known, with acids providednof phenolic groups, which have antioxidant properties. Thenfinal products 1 (formula 1) show that they continue to maintainnthe properties as angiotensin antagonists, whilenThey have the expected antioxidant properties. |