| abstract |
A compound of the formula (X), wherein: R13 is OR3, where R3 is C1 to C4 alkyl optionally substituted with one or two substituents selected from OH, C1 to C4 alkoxy, benzyloxy, NR5R6, phenyl, furanyl and pyridinyl; C3 to C6 cycloalkyl; 1- (C1 to C4 alkyl) piperidinyl; tetrahydrofuranyl or tetrahydropyranyl; R4 is SO2NR7R8; each of R5 and R6 is independently selected from H and C1 to C4 alkyl, or, together with the nitrogen atom to which they are attached, form a pyrrolidinyl, piperidinyl or morpholinyl group; R7 and R8, together with the nitrogen atom to which they are attached, form a 4-R10-piperazinyl group optionally substituted with one or two C1 to C4 alkyl groups and optionally in the form of their 4-N-oxide; and R10 is H; C1 to C4 alkyl optionally substituted with one or two substituents selected from OH, NR5R6, CONR5R6, phenyl optionally substituted with C1 to C4 alkoxy, benzodioxolyl and benzodioxanyl; C3 to C6 alkenyl; pyridinyl or pyrimidinyl or a salt of said compound, or an acid chloride derivative of said compound. |