abstract |
Microbial process for the preparation of the compound of ** formula ** from a substrate compound, in which R represents an alkali metal or an ammonium ion, comprising the following steps: a) cultivate a strain of the filamentous fungus species Mortierella maculata capable of 6รข-hydroxylate a compound in a nutritional medium containing sources of assimilable nitrogen and carbon and mineral salts, b) supply the substrate subject to transformation to the developed culture of Mortierella maculata, c) ferment the substrate until the end of the bioconversion, d) separate the compound from the culture broth, and e) isolate the compound. |