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filingDate 2000-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2005-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cffb8da3603c05452ba3ef4d44195027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d6b91b05f3a73580738bc909841d6de
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publicationDate 2005-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2239632-T3
titleOfInvention PIRIDAZINO-QUINOLINA DERIVATIVE AND METHOD FOR THE TREATMENT OF PAIN.
abstract It has now been discovered that a certain compound, which shows the property of binding to the glycine site of the NMDA receptor, has utility for pain relief, and particularly for the relief of neuropathic pain. Therefore, in one aspect, the invention provides a compound, 7-chloro-4-hydroxy-2- (2-chloro-4-methylphenyl) -1, 2, 5, 10-tetrahydropyridazino [4,5-b] quinolin-1, 10-dione, according to structural diagram I In another aspect, the invention provides a method for treating pain using a compound according to structural diagram I, the method comprising administering an effective amount of the pain relieving compound. In another embodiment, the method comprises administering an effective, pain-relieving amount of the compound according to structural diagram I, in the form of a pharmaceutical composition comprising a compound according to structural diagram I as active ingredient, together with one or more additives. pharmaceutically acceptable. In a further embodiment, the method comprises binding the compound of the invention to the glycine site of the NMDA receptor of a warm-blooded animal, such as a human being, to beneficially inhibit the activity of the NMDA receptor. Another aspect of the invention is a method for obtaining the compound according to structural diagram I. Still other aspects of the invention are pharmaceutical compositions containing the compound according to structural diagram I, and the use of the compound according to structural diagram I for the preparation. of medications and pharmaceutical compositions.
priorityDate 1999-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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