| abstract |
IN THE PRESENT INVENTION, FORMULA COMPOUNDS (I *) ARE DESCRIBED IN WHICH R 1 IS LOWER ALCOXYCARBONYL, R 2 IS LOWER SECONDARY OR TERTIARY RENT OR LOWER RENT RENTAL LOWER RENT, R 3 IS PHENYLL, WHICH IS OR NOT SUSTAINED BY A MORE RADICALS OF LOWER ALCOXI, OR C 4 -C 8, R 4 CYCLALKYL IS PHENYLL OR CYCLHEXYL, EACH OF THEM REPLACED IN POSITION 4 BY BINDED UNATURED HETEROYCLYCLES THROUGH A CARBON ATOM IN RING 8 ATOMOS IN RING, CONTAIN 1 TO 4 HETERO - SELECTED ATOMS BETWEEN NITROGEN, OXYGEN, SULFINYL (SULFONYL (- SO -) AND SULFONYL (- SO 2 -) AND FIND SUSTI TONE OR NOT REPLACED BY LOWER RENT - LOWER RENT - LOWER RENT, R 5, INDEPENDENTLY OF R 2, HAS ONE OF THE MEANINGS INDICATED FOR R 2, AND R 6, INDEPENDENTLY OF R 1, IS LOWER ALCOXICARBONYL, OR ITS SALTS, ON THE CONDITION OF LESS THAN A FORMING GROUP YOU GO OUT. THE COMPOUNDS ARE INHIBITORS OF THE PROTEASE OF THE RETROVIRAL ASPARTATE AND CAN BE USED, FOR EXAMPLE, IN THE TREATMENT OF AIDS. THESE COMPOUNDS PRESENT EXCELLENT PHARMACODYNAMIC PROPERTIES. |