http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2237495-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 |
| filingDate | 2000-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_014af903a7809fe14d11714dd20d8ffc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_473ed53cdd7ef13a1fa671e6cece5605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acb11a56e7b0de00618d7d856dd2160a |
| publicationDate | 2005-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2237495-T3 |
| titleOfInvention | USE OF PLEUROMULTILINE DERIVATIVES FOR THE TRANSDERMAL TREATMENT OF BACTERIAL DISEASES. |
| abstract | Use of a compound of the formula I where R1 is ethyl or vinyl; Y represents a group selected from COOH, -CH2-R2, and R2 is H, halogen, OH, NH2, SCN, N3, COOH, C (S) S- [alkyl with 1 to 5 carbon atoms], -S- pyridyl, -S-pyridyl substituted with one or two hydroxyl groups, alkylthio with 1 to 5 carbon atoms, alkylthio with 1 to 5 carbon atoms substituted with one or more amino, hydroxyl or carboxyl groups, -O-SO2- (4 -methylphenyl), -S- (CH2) mX, - (CH2- Z) r- (CH2) sQ, or -SC (CH3) 2-CH2-NH-C (O) -Q; or -S-C (CH3) 2- CH2-NH-C (O) -CH (NH2) -CH (CH3) 2; X is a saturated or unsaturated 5- to 6-membered heterocyclic ring that is attached to the -S- (CH2) m- group through a carbon atom and that contains one or more hetero groups selected from the group consisting of O, S, N o - N (R3); whereby said heterocyclic ring is unsubstituted or mono- or poly-substituted with one or more substituents selected from the group consisting of halogen, hydroxy, mercapto, alkyl with 1 to 5 carbon atoms, alkanoyl with 1 to 5 carbon atoms , alkylsulfoxyl with 1 to 5 carbon atoms, nitro, formyl, alkoxycarbonyl with 1 to 5 carbon atoms and hydroxyalkyl with 1 to 5 carbon atoms; R3 is hydrogen or alkyl with 1 to 5 carbon atoms; Q represents the group -N (R4) (R5) where R4 and R5 are independently from each other, alkyl with 1 to 5 carbon atoms or together with the nitrogen atom to which a 5- to 6-membered heterocyclic ring is attached saturated or unsaturated optionally containing a second hetero-moiety selected from sulfur or = N- (alkyl with 1 to 5 carbon atoms); Z is O, S or = N (alkyl with 1 to 5 carbon atoms); m is 0, 1, 2, 3, 4 or 5; r is 0 or 1; s is 2, 3, 4 or 5; in the form of a free base or in the form of a pharmaceutically acceptable salt, for the manufacture of a medicament for the transdermal treatment of bacterial infections in humans and animals. |
| priorityDate | 1999-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.