| abstract |
Compounds of the general formula ** (Formula) ** wherein R 1 is cyano, C 1-7 fluor-alkyl, C 1-7 alkoxy, C 1-7 fluor-alkoxy or is pyrrol-1-yl, which is unsubstituted or substituted with one to three substituents selected from the group consisting of fluorine, chlorine, cyano, phenyl optionally substituted with halogen, - (CH2) 1-4-hydroxyl, fluor-C1-7 alkyl, C1, 7 alkyl, - (CH2) n- C1-7 alkoxy, - (CH2) nC (O) OR¿, - (CH2) 1-4-NR¿R¿, hydroxy-C1-7 alkoxy, and - (CH2) n-CONR¿R¿; is hydrogen, if R1 is optionally substituted pyrrol-1-yl, as defined above, or is halogen, hydroxyl, C1-7 alkyl, fluorine C1-7 alkyl, C1-7 alkoxy, hydroxymethyl, hydroxyethoxy, C1 alkoxy , 7- (ethoxy) n (n = 1 to 4), C1-7 alkoxymethyl, cyanomethoxy, morpholin-4-yl, thiomorpholin-4-yl, 1-oxothiomorpholin-4-yl, 1, 1-dioxothiomorpholin-4- ilo, 4-oxo-piperidin-1-yl, 4-alkoxy-piperidin-1-yl, 4-hydroxy-piperidin-1-yl, 4-hydroxyethoxy-piperidin-1-yl, 4-C1-alkyl, 7-piperazin -1-yl. |