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filingDate 2003-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db4ce501978b1c7a5494b53b203c370b
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publicationDate 2005-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2234428-A1
titleOfInvention COMPOUNDS FOR THE TREATMENT OF THE DROUGHT OF THE EYE SURFACE CAUSED BY PHOTORREFRACTORY SURGERY.
abstract Compounds for the treatment of dryness of the ocular surface caused by photorefractive surgery. Agents that block the electrical activity of damaged nerve endings in the neuroma are useful for the treatment of ocular surface dryness caused by photorefractive surgery, such as excimer laser photorefractive kerectomy or laser-assisted in situ keratomileusis. Administration of such blocking agents, which include antiepileptics, anticonvulsants, antiarrhythmics, tricyclic antidepressants, and local anesthetics, and in particular include lidocaine, tocainide, phenytoin, carbamazepine, lamotrigine, and mexiletine, effectively reduce sensations of dryness. ocular.
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