abstract |
A compound of the ** formula ** wherein R is hydrogen, C1-C7 alkyl, hydroxy-C1-C7 alkyl, C1-C7 alkoxy C1-C7 alkyl, a cycloalkyl ring unsubstituted or substituted by hydroxyl containing 5 or 6 carbon atoms, a saturated 5- or 6-membered heterocyclic ring containing 1 to 3 ring heteroatoms selected from the group consisting of sulfur, oxygen or nitrogen, or an unsubstituted 5 or 6-membered heteroaromatic ring, joined by an atom carbon ring, containing 1 to 3 ring heteroatoms selected from the group consisting of sulfur, nitrogen and oxygen; R3 is cycloalkyl having 3 to 7 carbon atoms; R4 is a 5 or 6-membered unsubstituted or mono-substituted heteroaromatic ring, attached by a ring carbon atom to the amine group shown, whose 5 or 6-membered heteroaromatic ring contains 1 to 3 heteroatoms selected from sulfur, oxygen or nitrogen. |