abstract |
Composition for parenteral administration comprising, referred to by weight to volume, from 5% to 30% of a macrolide compound or a mixture of macrolide compounds; 1% to 10% of a low HLB surfactant having an HLB of 1 to 9 or a mixture of low HLB surfactants having an HLB of 1 to 9; from 1% to 20% of a co-solvent selected from the group consisting of an aromatic alcohol, a cyclic amide and mixtures thereof; and a solvent selected from the group consisting of triglycerides of C6-C14 medium chain fatty acids, glycol esters of medium chain fatty acids and mixtures thereof. |