| abstract |
A compound of the formula wherein R1 is from 1 to 3 substituents, each independently selected from the group consisting of hydrogen, halogen, C1-C6 alkyl and C1-C6 alkoxy; R2 is a radical chosen from the group formed by which R3 is selected from the group consisting of hydrogen, C1-C4 alkyl and -CF3; Ar1 is a radical chosen from the group consisting of in which R4 is from 1 to 3 substituents, each independently selected from the group consisting of hydrogen, halogen, hydroxy, -CF3, C1-C6 alkyl and C1-C6 alkoxy; R5 is from 1 to 2 substituents, each independently selected from the group consisting of hydrogen, halogen, C1-C6 alkyl and C1-C6 alkoxy; Ar2 is a radical chosen from the group formed by which R6 is from 1 to 3 substituents, each independently selected from the group consisting of hydrogen, halogen, -CF3, C1-C6 alkyl and C1-C6 alkoxy; R7 is from 1 to 2 substituents, each independently selected from the group consisting of hydrogen, halogen, C1-C6 alkyl and C1-C6 alkoxy; X is a radical chosen from the group consisting of in which Y is ¿O- or -CH2-; p is an integer from 1 to 4; R10 is selected from the group consisting of hydrogen and C1-C6 alkyl; and its stereoisomers and pharmaceutically acceptable salts thereof. |