| abstract |
Procedure for the continuous production of inhalable medicinal substances, comprising the following procedural steps: - use of a solution of drug substance (11), - segmentation of the solution by means of a segmenter and a means of transport (22), - to initiate and directing the crystallization process in a retention section (3), subjecting it to a defined temperature where, firstly, by a sudden reduction in temperature, the nucleation process is initiated so that the solution adopts a supersaturated state, metastable or labile with respect to the temperature T and the concentration C of the substance dissolved therein, and then the crystalline growth is influenced by directed cooling, and - separation of the crystalline particles from the other phases, after crossing the retention section in a separator. |