http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2230954-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7076dedc2d2a657bb9fccb6f5dbf0296 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2002-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2006-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92937c74ca96ce39c79ba42c9c00f92c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e71d22561bc644d52348efe3860f2af3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e11fecd241e83ba87bba0ac1eea9c81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cb4609dd60da4fe886adcd1c5325821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e1a246c1e6000a5624dd4248846a3a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4534527d3f26934708b7b3a2fd52c54 |
publicationDate | 2006-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2230954-B1 |
titleOfInvention | ISOENZYME-SPECIFIC ANTIBODIES AGAINST HUMAN GLUTAMINASE TYPES K AND L. |
abstract | Isoenzyme-specific antibodies against human glutaminase types K and L, useful to discover what type of glutaminase isoenzyme (K-PAG or L-PAG) is expressed in a tissue or cell type by contacting tissue sample or cells with a series of polyclonal antibodies (eg anti K-PAG, before L-PAG and synthetic anti-peptides of L-PAG), which recognize specific epitopes of each PAG isoenzyme. They are also useful for determining the regional, cellular and subcellular localization of both isoforms in mammalian tissue and cell samples, which would allow their use as marker reagents of specific cell populations, with great interest for example in the mammalian brain. Likewise, they are useful for comparing the isoenzymatic pattern in cancer patients with reference standards and determining qualitative or quantitative changes in glutaminase expression, with potential incidence on the patient's prognosis and clinical evolution. |
priorityDate | 2002-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 374.