| abstract |
Substituted derivatives of pyrrolidine-2, 3, 4-trione of general formula I, (I) in which: - the remainder R1 represents H, OR8, COR5, CSR5, NR6R7, COOR5, CONR6R7, CSNR6R7, a C1-10 residue alkyl, or an unsubstituted phenyl moiety. - the radicals R2, R3 are the same or different and represent H, F, Cl, Br, CF3, OR8, SR8, a C1-10 alkyl moiety, an aryl moiety, a heteroaryl moiety or an aryl moiety linked through a C1-6-alkylene group. - the R4 moiety means H, OH, OR8, SR8, COR5, COOR5, COCOR5, CONR6R7, CSNR6R7, or a C1-10 alkyl moiety. - the R5 moiety means H, a C1-10 alkyl moiety. - R6, R7 moieties are the same or different and represent H, OR8, COR5, COOR5, or a C1-10 alkyl moiety. - the R8 moiety represents a C1-10 alkyl moiety. in the form of its racemates, enantiomers, diastereoisomers or a base corresponding to a corresponding physiologically compatible salt. |