http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2226792-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4180fc57a693864e2ce2dbfd64a9278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-436 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate | 2000-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c84392f51b727c37aab4da3c62f7e56c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f318db6e268370071064ac36452201d |
| publicationDate | 2005-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2226792-T3 |
| titleOfInvention | THE USE OF DERIVATIVES OF 4-H-1-BENZOPIRAN-4-ONA AS INHIBITORS OF THE PROLIFERATION OF SMOOTH MIOCITS. |
| abstract | The use of a compound of ** formula ** where R1 is hydrogen, alkyl of 1 to 6 carbon atoms, aryl-C1-C4 alkyl; C1-C6 alkyl substituted with halogen, hydroxy or carboxy; C3-C6 cycloalkyl, pyridyl, thienyl, C3-C6 cycloalkyl-C1-C4 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, phenyl; phenyl, mono- or polysubstituted with halogen, C1-C4 alkyl, C1-C4 alkoxy, hydroxy, carboxy, COO-alkyl, CONH2, CONH-alkyl, CON (alkyl) 2, nitro, trifluoromethyl, amino, C1-C4-amino alkyl, di -C1-C4-amino alkyl, or phenyl; naphthyl, carboxyl, -CHO, COO-C1-C4 alkyl, a primary amino, alkylamino, aralkylamino, dialkylamino, amido, arylamino, diarylamino, or -CH2O-C1-C4 alkyl; R2 is hydrogen, alkyl with 1 to 6 carbon atoms, aryl, nitro, amino, di-C1-C4-alkyl, a halogen, hydroxy, alkoxy, -COOH, -COO-C1-C4 alkyl, -CHO, -CH2OH or -CH2O-C1-C4 alkyl, or one of its pharmacologically acceptable acid addition salts for the production of a pharmaceutical product for the inhibition of smooth muscle proliferation, where the dosage of the compound of formula 1 is less than 70%, preferably less than 60%, in particular less than 50% of the dosage that would be necessary to control cell growth. |
| priorityDate | 1999-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 261.