http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2226488-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-40 |
| filingDate | 1999-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbfe7bdefe3c6999bba572938e4f64d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbc38c2bf0bca5bb901e27ed63e22093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60cd739f6eb91dc30bfc5638d492db70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07c3ac90180a2bd989d40ac6e21201df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c32d827f1f519c8331a7722a452c3301 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_176a2e8dc745b36f64375a586b0024df |
| publicationDate | 2005-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2226488-T3 |
| titleOfInvention | USEFUL COMPOUNDS IN THE TREATMENT OF INFLAMMATORY DISEASES. |
| abstract | A compound of ** formula ** in which R1 and R2 independently represent (i) C1-6 alkyl, C3-8 cycloalkyl or C1-3 alkyl- C3-8 cycloalkyl, or such a group in which the alkyl or cycloalkyl it is substituted with one or more halogen groups, -CN, nitro, hydroxy or -O-C 1-6 alkyl; (ii) - (CH2) aAr1 or - (CH2) aOAr1; or NR1R2 together represent pyrrolidinyl, piperidinyl, piperazinyl, thiomorpholinyl, morpholinyl or azepinyl, or a group fused to a benzene ring, optionally substituted with one or more groups - (CO) n (CH2) tAr1, - (CO) n-alkyl C1-6-Ar1Ar2, - (CO) n-C1-6 alkyl, - (CH2) rOH, - (CH2) rO (CH2) pOH, - (CH2) rO-C1-6 alkyl, - O (CH2) tAr1 , - (CH2) rSO2Ar1, piperidin-1-yl, - (CH2) tCONR8R9, -NR10 (CO) n (CH2) tAr1, -NR10 (CO) n-C1-3 alkyl-C3-6 cycloalkyl, -NR10 ( CO) n-C1-6 alkyl-C3-6 dicycloalkyl, - CONR10 (CH2) tAr1, halogen, -NHSO2-C1-6 alkyl, - SO2NR10R11, -SO2-C1-6 alkyl or -SO2Ar2; R3 represents -C1-6 alkyl-NHC (= NH) NH2, -C2-6 alkenyl-NHC (= NH) NH2, -C2-6 -alkyl NHC (= NH) NH2, -C1-6 alkyl-NR14R18, - (CH2) nCONR14R18, - (CH2) nCOC-C1-6 alkyl, - (CH2) dCHNR18CONR20R21, - (CH2) mNR18CONR14R18, - (CH2) dNR18Ar3, - (CH2) dCONR18Ar3, - (CH2) CH018, - cAr3, -O (CH2) cAr3, -O (CH2) cAr3, - (CH2) dCO (CH2) aAr3 or - (CH2) dOAr3; or R3 represents - (CH2) c-2, 4-imidazolidinone, - (CH2) c (piperidin-4-yl), - (CH2) c (piperidin-3-yl), - (CH2) c (piperidin-2 -yl), - (CH2) c (morpholin-3-yl) or - (CH2) c (morpholin-2-yl) optionally substituted on nitrogen with - (CO) f-C1-6 alkyl, - (CO) f (CH2) cAr2 or - (C (= NH) NH2. |
| priorityDate | 1998-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 439.