| abstract |
A compound of formula ** (Formula) ** an N-oxide form, a pharmaceutically acceptable addition salt or a stereochemically isomeric form thereof, in which: each R1 is independently hydrogen, halogen, C1-6alkyl, nitro, hydroxy or C1-4alkyloxy; Alk is C1-6alkanediyl; n is 1 or 2; D is 1- or 2-benzimidazolyl, 2 (3H) benzoxazolone-3-yl or a radical of formula ** (Formula) ** in which each X independently represents O, S or NR12; R2 is hydrogen, C1-6alkyl, aryl or aryl-C1-6alkyl; R3 is hydrogen, C1-6alkyl, C1-6alkyloxy, C1-6alkylthio, amino or mono- or ddi (C1-6alkyl) amino; R4, R5, R6, R7, R8, R10, R11 and R12 are each independently hydrogen or C1-6alkyl; R9 is hydrogen, C1-6alkyl or aryl; or R3 and R4, taken together, can form a bivalent radical -R3-R4- of the formula CH2-CH2-CH2 (a-1); -CH2-CH2-CH2-CH2 (a-2); -CH = CH-CH2 (a-3); -CH2 - CH = CH (a-4). |