http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2223827-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 |
| filingDate | 2001-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1920bdcaa7ad9433dcdaf93351301434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a0ad96b57435808128aa3ec4899150e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_558421921d94e029a545177436ed8039 |
| publicationDate | 2005-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2223827-T3 |
| titleOfInvention | USEFUL THIOPHEN DERIVATIVES AS ANTI-BANERIGIN AGENTS. |
| abstract | A compound of ** formula ** or a pharmaceutically acceptable salt, prodrug or hydrate thereof, formula in which X is N, CH or C (CN); Y is N, CH, CF, or NO; R1 is H or C1-C6 alkyl; R2 is 5-13 membered heterocycle, R2 group which is optionally substituted with 1 to 5 R5 substituents; Each R5 is independently selected from halo, cyano, trifluoromethoxy, trifluoromethyl, -C (O) R8, - NR6C (O) R7, -C (O) NR6R7, -NR6R7, -OR9, -SO2NR6R7, - SO2R6, -NR6SO2R7, -NR6SO2NR9R10, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, - (CH2) jO (CH2) qNR6R7, - (CH2) tO (CH2) qOR9, - (CH2) tOR9, -S (O) j (C1-C6 alkyl), - (CH2) t- (C6-C10 aryl), - (CH2) t (5-10 membered heterocycle), - (CH2) tO (CH2) q (5-10 membered heterocycle ), -C (O) (CH2) t (5-10 membered heterocycle), - (CH2) jNR7 (CH2) qNR6R7, - (CH2) jNR7CH2C (O) NR6R7, - (CH2) jNR7 (CH2) qNR9C ( O) R8, - (CH2) jNR7 (CH2) tO (CH2) qOR9, - (CH2) jNR7 (CH2) qS (O) j (C1-C6 alkyl), - (CH2) jNR7 (CH2) tR6, - SO2 (CH2) t (C6-C10 aryl), and -SO2 (CH2) t (5-10 membered heterocycle), in which j is an integer from 0 to 2, t is an integer from 0 to 6, q is an integer from 2 to 6, the residues - (CH2) q- and - (CH2) t- of the preceding R5 groups optionally include a double or triple carbon-carbon bond when t is an integer from 2 to 6 , and the remains to alkyl, aryl and heterocycle of the preceding R5 groups are optionally substituted with 1 to 3 substituents independently selected from halo, cyano, trifluoromethyl, -C (O) R8, -NR6C (O) R7, - C (O) NR6R7, - (CH2) tNR6R7, -SO2R6, -SO2NR6R7, C1-C6 alkyl, - (CH2) t (5-10 membered heterocycle), - (CH2) tO (CH2) qOR9, and - (CH2) tOR9, in which t is an integer from 0 to 6, and q is an integer from 2 to 6. |
| priorityDate | 2000-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 760.