abstract |
Prion protein detection procedureninfectives (PrP Sc) by spectroscopynRaman-laser.n n n The present invention provides a method, by Raman-laser spectroscopy, for the detection of infectious prion proteins (PrP Sc) in biological samples of affected animals of a TSE, and their application is extensible to blood of, among others, bovines , goats, humans and birds. The process of this invention, qualitative and quantitative, includes a first step aimed at obtaining the blood fraction where the infectious prion proteins are more concentrated. The results obtained by the procedure described in this invention on prion analysis have 100% agreed with the post-mortem biodiagnostic tests of brain samples made in the corresponding animals from which blood extractions were performed. |