http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2222593-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4418 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 |
| filingDate | 1998-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b7a4863d0c9a0b1498faaddcb407c9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_121926c0ab1c3c37795c4fe4c4227c2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54c96cb594dfc4be58de4205c6daa9a4 |
| publicationDate | 2005-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2222593-T3 |
| titleOfInvention | USE OF CERTAIN TETRAHYDROPIRIDINES FOR THE PREPARATION OF MEDICINES FOR THE TREATMENT OF DISEASES THAT CAUSE THE DESTRUCTION OF MYELINE. |
| abstract | The invention relates to the use of tetrahydropyridine derivatives of formula (I) in which: R {sub, 1} represents a halogen or a CF group {sub, 3}, C {sub, 1} -C {sub alkyl, 4} or C {sub, 1} -C {sub, 4} alkoxy; Y represents a nitrogen atom or a CH group; each of Z '' and Z "represents hydrogen or a C {sub, 1} -C {sub, 3} alkyl group, or one represents hydrogen and the other a hydroxy group, or the two together represent an oxo group; Z represents a phenyl radical; a phenyl radical monosubstituted with a substituent X, where X (a) is a C {sub, 1-6} alkyl, C {sub, 1-, 6} alkoxy, C {sub, 3-7 carboxyalkyl group }, C {sub, 1-4} alkoxy, C {sub, 1-6} carbonylalkyl, C {sub, 3-7} carboxyalkoxy or C {sub, 1-4} alkoxyC {sub, 1-6} carbonyloxy ; (b) a group selected from a C {sub, 3-7} cycloalkyl group C {sub, 3-7}, C {sub, 3-7} methyl cycloalkyl, C {sub, 3-7} cycloalkyl group amino and cyclohexenyl, said group being capable of being substituted by a halogen, hydroxy, C {sub, 1-4} alkoxy, carboxy, C {sub, 1-4} carbonyl, amino, mono- or dialkyl C {sub, 1 -4} amino; or (c) a group selected from a group phenyl, phenoxy, phenylamino, N-alkyl C {sub, 1-3} phenylamino, phenylmethyl, phenylethyl, phenylcarbonyl, phenylthio, phenylsulfonyl, phenylsulfinyl or styryl, said mono- or polysubstituted group may be in the phenyl group with a halogen, CF {sub, 3}, C {sub, 1-4} alkyl, C {sub, 1-4} alkoxy, cyano, amino, mono- or di-C {sub, 1-4} amino, acyl C {sub, 1-4} amino, carboxy, C {sub, 1-4} carbonyl, aminocarbonyl, mono- or dialkyl C {sub, 1-4} aminocarbonyl, C {sub, 1-4} aminoalkyl, C {sub, 1-4} hydroxyalkyl or C {sub, 1-4} haloalkyl; a phenyl radical disubstituted with a substituent R {sub, 2}, R {sub, 2} being a halogen or a hydroxy, methyl, ethyl group, C {sub, 3-6} alkyl, C {sub, 1-4 alkoxy } or trifluoromethyl and with a substituent X, where X is as defined above; a 1-naphthyl or 2-naphthyl radical; a 1-naphthyl or 2-naphthyl radical, substituted at positions 5, 6, 7 and / or 8 with one or two hydroxyl groups, one or two C {sub, 1-4} alkoxy groups, or a 6,7- group methylenedioxy; or Z "is hydrogen and each of Z and Z" independently represents an unsubstituted or mono-, di- or trisubstituted phenyl group; or one of its pharmaceutically acceptable salts or solvates, to prepare pharmaceutical compositions to combat diseases that produce demyelination |
| priorityDate | 1997-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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