http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2220185-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26db05f349a12e10706b1e5ea02c860a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dedcce24ab96003cdfab01f45a0ede01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4294e59a8b8b7687c4f8aeeb8f65e03e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate | 2002-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ad6edce7645c4ef5ba692410eafed69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65a86b0ea7f28b33341230041d63a2b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd046e03eb54464e6e20712b899e3d29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_511906ee173589d2bc54e1f2c4b0e838 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f355594980fb600f5a117809bea184f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be258508a60533e3858a9eed1422b282 |
| publicationDate | 2004-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2220185-A1 |
| titleOfInvention | NEW INHIBITOR PEPTIDE OF THE NA + / H + EXCHANGER (PINHE), AND ITS APPLICATIONS. |
| abstract | New peptide exchanger inhibitornNa + / H + (PINHE), and its applications.n n n The present invention describes a peptide (PINHE)nconsisting of 28 amino acids obtained by fractionation andnpurification of the culture supernatant of Haloferax gibbonsiinAlicante SPH7. PINHE acts as a natural physiological inhibitornof the Na + / H + exchanger in eukaryotes. It is active innwide ranges of salt concentrations, temperature and pH,nTrypsin resistant and pronase sensitive. Of its reversible actionnon the Na + / H + exchanger derives: (1) its use fornthe treatment or prophylaxis of diseases such as diseasesncardiovascular, renal, cerebral, metabolic, processesnproliferative pathologies, hyperproduction of hydrochloric acidnetc., (2) in other diseases or pathologies that occur withnischemia and post-ischemic reperfusion injuryndue to NHE hyperactivity as ischemia due to alterationsnprimary or secondary vascular in various tissues, bynpost-infarction reperfusion, by organ transplantationnor tissues, etc. Also as a contraceptive (in male mammals),nantibiotic or immunoregulatory agent, and in plants as a modulatornof saline stress |
| priorityDate | 2002-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 135.