http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2217159-T3

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filingDate 2001-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0450394004f249558cf94a7361e60ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98857dd2203d1f63797f4c1742244a53
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publicationDate 2004-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2217159-T3
titleOfInvention CARBAMATE DERIVATIVES AND PODOFYLOTOXINE THIOCARBAMATE, ITS PREPARATION PROCEDURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
abstract Compounds of Formula (I): ** (formula) ** in which: - R1 represents a group selected from hydrogen, linear or branched alkyl of 1 to 6 carbons, aryl, aryl (C1-C6) linear or branched, heteroaryl , linear or branched (C1-C6) heteroarylalkyl, linear or branched alkoxycarbonyl of 1 to 6 carbon atoms, aryloxycarbonyl, linear or branched arylalkoxycarbonyl of 1 to 6 carbon atoms, heterocycloalkoxycarbonyl, linear or branched alkylsulfonyl of 1 to 6 carbon atoms , arylsulfonyl, linear or branched arylalkyl sulfonyl of 1 to 6 carbon atoms, and phosphonic group, - R2 represents an oxygen atom or a sulfur atom, - R3 represents a hydrogen atom, a linear or branched alkyl group of 1 to 6 carbon atoms, cycloalkyl, or linear or branched arylalkyl of 1 to 6 carbon atoms, - X represents a linear or branched alkylene group of 1 to 6 carbon atoms, - R4 represents a group selected from: amino ev Entity substituted by one or two groups, identical or different, selected from linear or branched alkyl of 1 to 6 carbon atoms, aryl and linear or branched arylalkyl of 1 to 6 carbon atoms, a group of formula -N (R3) - X1-OR5 in which R3 is as defined above, X1 represents a linear or branched alkylene group of 1 to 6 carbon atoms and R5 represents a group selected from a hydrogen atom, a linear or branched alkyl group of 1 to 6 carbon atoms, a linear or branched aryl and arylalkyl group of 1 to 6 carbon atoms; Does a group of the formula -N (R3) -X1-NR6R7 in which R3 and X1 are as defined above and R6 and R7, identical or different, each represent a group selected from a hydrogen atom, an alkyl group linear or branched of 1 to 6 carbon atoms, an aryl and a linear or branched arylalkyl of 1 to 6 carbon atoms; ¿Hydroxyl, linear or branched alkoxy of 1 to 6 carbon atoms, ¿aryloxy, ¿a group of formula -O-X1-OR5 in which R5 and X1 are tale as defined above, and a group of formula - O-X1-NR6R7 in which R6, R7 and X1 are as defined above, their isomers, as well as their addition salts of a pharmaceutically acceptable acid or base.
priorityDate 2000-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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