| abstract |
Compound of formula (I) in which: R1, R2, R3, R4, R5, R6 and R8, identical or different, each represent a hydrogen atom or a linear or branched (C1-C6) alkyl group, aryl- linear or branched ((C1-C6) alkyl, hydroxyl, linear or branched (C1-C6) linear or branched (C1-C6) alkoxy, linear or branched (C1-C6) acyl-oxyl, aryl-carbonyl -oxy, linear or branched (C1-C6) alkyl or carboxy, R7 represents a hydrogen atom or a linear or branched hydroxyl, C1-C6 alkoxy, linear or branched aryl-C1-C6 alkoxy , linear or branched acyl-oxyl (C1-C6) or aryl-carbonyl-oxyl, or one of the groups R1a R8 forms with another group R1 to R8 contiguous an alkyloxy ((C1-C2) alkyl group, its optical isomers when they exist , as well as its addition salts of a pharmaceutically acceptable acid or base, with the proviso that: - at least one of the groups R1 to R8 represents a linear, branched hydroxyl, (C1-C6) alkoxy group icado, linear or branched (C1-C6) acyloxy or aryl-carbonyl-oxyl, - and that the compounds of formula (I) are different from 1,3-dimethoxy-6H-isoindolo- [2,1-a] - indole-6-one. |