| abstract |
THE INVENTION REFERS TO NEW DISCLOSED BICYCLIC HETEROCICLES OF GENERAL FORMULA (I): RA - A - HET - B AR - E, IN WHICH A, B, AR, HET YRA ARE DEFINED AS IN CLAIM 1. THE INVENTION TREATS EQUALLY OF ITS TAUTOMERS, ITS STEREOISOMERS, ITS BLENDS AND ITS SALTS, THAT HAVE VALUABLE PROPERTIES. THE COMPOUNDS OF THE CITED GENERAL FORMULA (I), IN WHICH E IS A CIANO GROUP, REPRESENTS ASSOCIATE VALUABLE INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF THE OTHER COMPOUNDS OF THE GENERAL FORMULA (I). IN ADDITION, THE COMPOUNDS OF THE CITED GENERAL FORMULA (I) IN WHICH E MEANS A GROUP R SUB, B NH - C (= NH), HAVE PHARMACOLOGICAL PROPERTIES OF GREAT VALUE, IN PARTICULAR TO INHIBIT THE THROMBIN AND EXTEND THE THROMBIN TIME . |