http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2198907-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_981a37900e6991fb373304ed2ba5a703 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-61 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-61 |
| filingDate | 1999-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8771a02212b5333f2ba03f0026a884d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef852e07a4af5d9b39b65cbfe420495d |
| publicationDate | 2004-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2198907-T3 |
| titleOfInvention | PROCEDURE FOR OBTAINING 2-NITROGUANIDINS 1,3-DISUBSTITUIDAS. |
| abstract | Process for obtaining compounds of the formula (I) ** FORMULA ** in which R1 means hydrogen or alkyl with 1 to 4 carbon atoms, R2 means hydrogen, alkyl with 1 to 6 carbon atoms, cycloalkyl with 3 to 6 carbon atoms or a moiety -CH2R3, R3 means alkenyl with 2 to 5 carbon atoms, alkynyl with 2 to 5 carbon atoms, phenyl, cyanophenyl, nitrophenyl, halogenophenyl with 1 to 3 carbon atoms, phenyl substituted by alkyl with 1 to 3 carbon atoms, for halogenalkyl with 1 to 3 carbon atoms with 1 to 7 halogen atoms, for alkoxy with 1 to 3 carbon atoms or for halogenoalkoxy with 1 to 3 carbon atoms and 1 to 7 halogen atoms , 5-thiazolyl, 55-thiazolyl substituted by one or two (preferably one) substituents of the group consisting of alkyl with 1 to 3 carbon atoms, halogenoalkyl with 1 to 3 carbon atoms with 1 to 7 halogen atoms, cyclopropyl, halogenocyclopropyl , alkenyl with 2 to 3 atoms os carbon, alkynyl with 2 to 3 carbon atoms, alkoxy with 1 to 3 carbon atoms, halogenoalkenyl with 2 to 3 carbon atoms with 1 to 4 halogen atoms, halogenoalkynyl with 2 to 3 carbon atoms with 1 to 3 atoms halogen, halogenoalkoxy with 1 to 3 carbon atoms with 1 to 7 halogen atoms, alkylthio with 1 to 3 carbon atoms, halogenoalkylthio with 1 to 3 carbon atoms with 1 to 7 halogen atoms, allyloxy, propargiloxy, allylium, propargylthio, halogenoaryloxy, halogenoalkyl, halogen, cyano or nitro; or means 3-pyridyl substituted by one to four (preferably one or two) residues of the group consisting of halogenoalkyl with 1 to 3 carbon atoms with 1 to 7 halogen atoms, propyl cycle, halogenocyclopropyl, alkenyl with 2 to 3 carbon atoms, alkynyl with 2 to 3 carbon atoms, halogenoalkenyl with 2 to 3 carbon atoms with 1 to 4 halogen atoms, halogenoalkynyl with 2 to 3 carbon atoms with 1 to 3 halogen atoms, halogenoalkoxy with 1 to 3 carbon atoms with 1 to 7 halogen atoms, alkylthio with 1 to 3 carbon atoms, halogenoalkylthio with 1 to 3 carbon atoms with 1 to 7 halogen atoms, allyloxy, propargiloxyalylthio, propargylthio, halogenoalyloxy, halogenoalkyl, cyano, nitro, alkyl with 1 to 3 carbon atoms, alkoxy with 1 to 3 carbon atoms or halogen, Het means an unsubstituted or substituted, aromatic or non-aromatic, monocyclic or bicyclic moiety preferably a series moiety consisting of ** FORMU LA ** which may contain one or two substituents of the group consisting of halogenoalkyl with 1 to 3 carbon atoms with 1 to 7 halogen atoms, cyclopropyl, halogenocyclopropyl with 1 to 3 halogen atoms, alkenyl with 2 to 3 carbon atoms, alkynyl with 2 to 3 carbon atoms, halogenoalkenyl with 2 to 3 carbon atoms with 1 to 4 halogen atoms, halogenoalkynyl with 2 to 3 carbon atoms with 1 to 3 halogen atoms, halogenoalkoxy with 1 to 3 carbon atoms with 1 to 7 halogen atoms, alkylthio with 1 to 3 carbon atoms, halogenoalkylthio with 1 to 3 carbon atoms with 1 to 7 halogen atoms, allyloxy, propargiloxy, allyl, propargylthio, halogenoalyloxy, halogenoalkyl, cyano, nitro, alkyl with 1a 3 carbon atoms, and halogen, characterized in that a compound of the formula (II) is reacted ** FORMULA ** in which R1, R2 and Het have the meanings indicated above and R4 means, respectively unsubstituted or substituted, alkyl with 1 to 10 carbon atoms, cycloalkyl with 3 to 6 carbon atoms, phenyl, arylalkyl or heterocyclyl an unsaturated or saturated heterocycle with 5 or 6 members in the ring with one or more heteroatoms of the group consisting of nitrogen, oxygen , sulfur, such as, for example, furan, tetrahydrofuran, thiophene or pyridine, if necessary in the presence of a diluent, with compounds of the formula (III) R5-NH2 (III) in which R5 means, respectively substituted as appropriate, alkyl, cycloalkyl, aryl, arylalkyl or heterocyclylmethyl, heterocyclyl meaning an unsaturated or saturated heterocycle with 5 or 6 ring members with one or more heteroatoms of the series consisting of nitrogen, oxygen, sulfur, such as, for example, furan, tetrahydrofuran, thiophene or pyridine |
| priorityDate | 1998-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.