abstract |
Substituted cycloheptenes of the general formula I wherein R1 means OH, O- (C1-6) -alkyl, O- (C3-7) -cycloalkyl, O-aryl, C1-6-alkyl-COO-, aryl- COO- , R2 means C1-6-alkyl, (CH2) (1-2) -aryl, C2- 6-alkenylene-aryl, and R3 means (CH2) (0-1) -C5-7-cycloalkyl, (CH2) ( 0-2) -aryl, heterocyclyl, C1-6-alkyl-heterocyclyl, or these are in the form of their enantiomers, diastereomers, racemates, bases or as salts of physiologically compatible acids, and the expression "aryl" means unsubstituted phenyls or phenyls substituted once or several times with OH, F, Cl, CF3, C1-6-alkyl, C1-6-alkoxy, C1-7-cycloalkoxy, C3-7-cycloalkyl, C2-6-alkenylene, heterocyclyl or phenyl, and the heterocyclyl or phenyl moieties may be linked by condensation where appropriate, and the expression "heterocyclyl" means 5- or 6-membered heterocyclic compounds, saturated or unsaturated, where appropriate provided with an aryl system linked by condensation, containing 1 or 2 heteroatoms of the group consisting of nitrogen, oxygen and / or sulfur. |