http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2186469-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7076dedc2d2a657bb9fccb6f5dbf0296 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate | 2000-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e11fecd241e83ba87bba0ac1eea9c81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e1a246c1e6000a5624dd4248846a3a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4f3b3fb0f35fd4f90e167bf6ce04dc4 |
| publicationDate | 2004-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2186469-B1 |
| titleOfInvention | GENETICALLY MODIFIED VIABLE TUMOR CELLS, TO PARTIALLY INHIBIT THE EXPRESSION OF PHOSPHATE ACTIVATED GLUTAMINASE ENZYME (PAG) AND ITS APPLICATION AS AN ANTITUMORAL VACCINE. |
| abstract | Modified viable tumor cellsngenetically, to partially inhibit enzyme expressionnphosphate activated glutaminase (PAG) and its application as a vaccinenantitumorn n n A procedure for stimulation is describednof the animal immune system, when used as a vaccinenviable but genetically modified tumor cells bynantisense techniques. Said gene manipulation is directed, innspecifically, to inhibit the expression of an enzyme that is key in thensurvival, proliferation and manifestation of propertiesnPhenotypic of all tumor cells: the mitochondrial enzymenphosphate activated glutaminase (PAG). With this method you getngenerate long-term immunity against murine cancers and itnenables the potential use of the immunized animal, such asnbiological experimentation model. This invention fitsnwithin the field of tumor immunotherapy. |
| priorityDate | 2000-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 186.