| abstract |
THIS INVENTION PROVIDES NEW FORMULA BENZOTIOPHENE COMPOUNDS I: IN WHICH: R {SUB, 1} IS O (RENT C {SUB, 1} {SUB, 6}), CO STITUTED, OB, 2} ES (RENT C {SUB, 1} NONLY REPLACED, OPTIONALLY REPLACED NILE, OR, 4} CH {SUB, 2} NR {SUB, 3} R {SUB, 4}; R {SUB, 3} YR {SUB, 4} ARE EACH ONE INDEPENDENTLY RENT C {SUB, 1} TO FORM, WITH THE NITROGEN TO WHICH THEY ARE UNITED, PIPERIDINYL, PIRROLIDINYL, METHYL-PIRROLIDINYL, DIMETHYL PIRROLIDINYL OR HEXAMETILENIMINE; , IN PARTICULAR OSTEOPOROSIS, PATHOLOGICAL STATES RELATED TO THE CARDIOVASCULAR SYSTEM INCLUDING HYPERLIPIDEMIES AND RELATED CARDIOVASCULAR PATHOLOGIES, AND CANCER DEPENDENT ON STROGEN. |