| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4418
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate |
1998-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b062f582e0edaad059dc1b6222c82fb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a6fb01b42757520ffedc6a38a98d877
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7d7a17bda5e3d1f3e68b51e9e711cc1 |
| publicationDate |
2002-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2178300-T3 |
| titleOfInvention |
BISULFATE SALT OF THE HIV PROTEASE INHIBITOR. |
| abstract |
The present invention provides a novel crystalline bisulfate salt of the HIV protease inhibitor azapeptide of formula ** (Formula) ** showing unexpected solubility / dissolution in water superior to those of other salts, and which better or significantly oral bioavailability in animals compared to the free base. The bisulfate salt is therefore useful in pharmaceutical forms of the aforementioned protease inhibitor, in particular in oral pharmaceutical forms. |
| priorityDate |
1998-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |