| abstract |
Derivatives of 4-phenyl-pyridine. These compounds correspond to the general formula (I) where the radicals R, R {sup, 1}, R {sup, 2}, R {sup, 2 ''}, R {sup, 3}, R {sup, 4}, X, n and m are as expressed in the claims. These compounds show a higher affinity for the NK-1 receptor. The invention also relates to salts derived from the compounds that are pharmaceutically acceptable, to medicaments containing one or more of these compounds, and to a process for the preparation of the compounds. The products of the invention can be used for the treatment of diseases related to NK-1 receptor antagonists. |