| abstract |
A PHARMACEUTICAL COMPOSITION IS DESCRIBED, INCLUDING: I) AN ANTIFUNGIC AGENT THAT IS THE (-) - (2R - CIS) - 4 - [4 - [4 - [4 - [[- 5 - (2,4 - DIFLUORFENILE) - TETRAHIDRO - 5 - (1H 1,2,4 - TRIAZOL - 1 - ILMETIL) FURAN - 3 - IL] METOXI] PHENYL] - 1 - PIPERAZINIL] PHENYL] - 2,4 - DIHYDRO - 2 - [(S) - 1 - ETIL 2 (S) - HYDROXIPROPIL] - 3H - 1,2,4 - TRIAZOL - 3 - ONA; II) AT LEAST A NON-IONIC TENSIOACTIVE AGENT; AND III) A DILUENT. THE COMPOSITION ALLOWS THAT THE ANTIFUNGIC COMPOUND, THAT HAS A VERY LOW WATER SOLUBILITY, IMPROVES AND REINFORCES ITS BIODISPONIBILITY IN MAMMALS, AS FOR EXAMPLE HUMANS. |