| abstract |
New indolylpiperidine derivatives as antihistamine and antiallergic agents of formula (1) ** FORMULA ** wherein A {sup, 1} represents an alkylene, alkyleneoxy, alkylene, alkyleneamino, alkanoyl or hydroxyalkylene group; A {sup, 2} represents a single bond, an alkylene or alkenylene group; W represents a single bond, or a phenylene or furanylene group optionally substituted by one or more halogen atoms, or alkoxy or alkyl groups; R {sup, 1} represents a hydrogen atom or an alkyl, alkoxyalkyl, alkoxy-alkoxyalkyl or phenylalkyl group where the phenyl ring is optionally substituted by one or more halogen atoms or alkyl or alkoxy groups; R {sup, 2} represents a hydrogen or halogen atom, or an alkyl, alkoxy, amino, aminoalkyl, thioalkyl or alkanoyl group; and R {sup, 3} represents a carboxyl group or a tetrazole group; |