abstract |
Compounds of formula I, R {sup, 1} O {(} O {C-CH2 - {(} R {Cgl-Aze-Pab-R {sup, 2}, wherein R {sup, 1} are provided and R {sup, 2} have the meanings given in the memory, which are useful as prodrugs of trypsin-like protease inhibitors, such as thrombin, and in particular in the treatment of conditions where thrombin inhibition is necessary (by example thrombosis) or as anticoagulants. |