| abstract |
CCR-3 receptor antagonist pyrrolidine derivatives. These antagonists are formed by pyrrolidine derivatives, of formula (I), where the radicals R {sub, 1}, Ar {sup, 1}, Ar {sup, 2}, A, B, Z and Q have the meaning expressed in the claims. The invention also relates to pharmaceutical compositions containing these CCR-3 receptor antagonists, to methods for their use and to methods for preparing said compounds. These products are used to treat respiratory diseases, such as asthma. |