http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2120881-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2ff3e8c2e8401e6b90f3ac6ba215e94 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-06 |
| filingDate | 1996-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_136fd2d7c5bbaf10d4695a22b62c9deb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bafc6b25afd2491bc0cb762de29abda4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db63aad94343694ad66ad4b27d7e92c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54603cd29be08eb971aa639b838eff4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26472040f2827a28713ff2cf42b98884 |
| publicationDate | 1998-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2120881-A1 |
| titleOfInvention | ENANTIOMERS OF 5-METHYL-1, 3-TIAZIN-2, 4-DIONA AND ITS USE IN THE INTERMEDIATE SYNTHESIS OF CHIRAL PHARMACES. |
| abstract | Enantiomers of 5-methyl-1,3-thiazine-2,4-dione and their use in the synthesis of chiral drug intermediates. The enantiomers of 5-methyl-1,3-thiazine-2,4-dione (I) are suitable for the synthesis of chiral pharmaceutical active ingredient intermediates. In particular, the S-enantiomer of (I) is useful for the synthesis of S-(-)-3-acetylthio-2-methylpropionic acid (S-AMPA), a precursor to Captopril. These enantiomers can be obtained by stereoselective enzymatic hydrolysis of the racemic 5-methyl-1,3-thiazin-2,4-dione in the presence of a biocatalyst that contains enzymes capable of stereoselectively hydrolyzing said racemic mixture. |
| priorityDate | 1996-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.