| abstract |
ACID DERIVATIVES FENILOCARBOXILICO HAVING A HETERO ring as substituent of the formula wherein R1 is halogen, alkyl, cycloalkyl, hydroxyl, alkoxyl, phenoxyl, which has substituents selected from halogen or carboxyl, ALQUILOSULFONILOOXILO, FENILOSULFONILOOXILO optionally substituted by halogen , ALQUILOSULFONILOOXIALCOXILO, amino, alkanoylamino, benzoylamino, ALQUENILOOXILO, FENILOALCOXILOALCOXILO, HIDROXILOALCOXILO, FENILOALCOXILO with optionally 1 to 3 substituents selected from halogen, alkyl and alkoxy, halogenoalkyl, CICLOALQUILOOXILO optionally substituted by hydroxyl, alkoxyl substituted by cycloalkyl optionally having hydroxyl substituent, IMIDAZOLILOALQUILO , OR IMIDAZOLYLALCOXYL; K IS 0 O FROM 1 TO 3; O (R1) K IS ALKYLENODIOXYL; A IS ALKYLENE OR ALKYLENOOXYL; L IS 0 O 1; B IS METHYLENE OR CARBONYL; M IS 0 O 1; D IS ALKYLENE; E IS ALKYLENE OR ALKYLENE; N IS 0 O 1; AND R2 IS HYDROGEN OR ALKYL, OR A SALT OF THEM, WHICH HAS A FATTY ACID SYNTHESIS INHIBITING ACTIVITY, CHOLESTEROL SYNTHESIS INHIBITING ACTIVITY AND ARE USED AS ANTI-LIPIDEMIC AGENTS, PROPHYLACTIC AGENTS AND TREATMENT AGENTS OF TREATMENT OF OBESITY AND AS ANTI-DIABETICS. |