| abstract |
NEW TETRALONAS OF GENERAL FORMULA I, USEFUL AS REGULATORS OF THE CONTRACTION OF THE SMOOTH MUSCULATURE IN THE CARDIOVASCULAR, BRONCOPULMONARY AND DIGESTIVE SYSTEMS, WHERE RBS1 SC AND RBS2 SC SIGN HIDROGYN, HIDROGENO, CS1 HXI4 HXI; RBS3 SC AND RBS4 SC REPRESENT CSI1-4 SC ALKYL, OR RBS3 SC AND RBS4 SC TOGETHER FORM A CHAIN OF CSI2-5 SC POLYMETHYLENE; RBS5 SC IS HYDROGEN IN WHICH CASE RBS6 SC IS HYDROGEN, HYDROXYL OR CSI1-4 SC ALCOXI, OR RBS5 SC IS HYDROXYL AND THEN RBS6 SC IS HYDROGEN, OR RBS5 SC-RBS6 SC IS ALONG WITH THE DUAL CARBON FORDS OR AN EPOXIDE TYPE GROUP; RBS7 SC IS A 2-, 3- OR 4-PYRIDYL GROUP THAT MAY BE OPTIONALLY REPLACED BY A HYDROXYL GROUP OR WHOSE NITROGEN ATOM MAY BE OPTIONALLY IN THE FORM OF N-OXIDE; AND ITS SALTS THE PRESENT INVENTION ALSO DESCRIBES PROCEDURES FOR THEIR OBTAINING AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |