| abstract |
A DEFEM COMPONENT OF THE FORMULA: WHERE R1 IS AMINO OR A PROTECTED AMINO, R2 IS UNDER ALKIL WHICH MUST HAVE ONE OR MORE SUITABLE SUBSTITUTES, R3 IS COO (THETA), CARBOXI OR A PROTECTED CARBOXI, R4 IS HYDROXY (LOW ALKIL O HYDROXY (LOW) PROTECTED ALKIL, R5 IS AMINO OR A PROTECTED AMINO, R6 IS HYDROGEN OR LOW ALKIL, X (THETA) IS AN ANION AND N IS 0 OR 1, PROVIDED THAT: (I) WHEN R3 IS COO (THETA), THEN N IS 0 AND (II) WHEN R3 IS CORBOXI OR A PROTECTED CARBOXI, THEN N IS 1. AND PHARMACEUTICALLY ACCEPTABLE SALTS OF THEM, THE PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS WHICH ARE UNDERSTANDING AS ACTIVE INGREDIENTS WITH PORTABLE MIXTURES. |