abstract |
Procedure for preparing thiazepine compounds with antidopaminergic activity, of formula II: ** formula ** or a salt thereof, characterized in that it comprises: (a) reacting an imonochloride of formula IV: ** formula ** with 1-hydroxyethoxyethylpiperazine; or (b) reacting a thioether of formula VII: ** formula ** with a piperazine of formula V: ** formula **, and then when the compound of formula II is obtained in the form of a base and a salt, said compound of formula II obtained in the form of a base is reacted with an acid, to obtain a salt and, when the compound of formula II is obtained as a salt and a base is required, said compound of formula II is neutralized , obtained in the form of a salt, to provide said base. |