| abstract |
METHOD OF PRODUCING 1,1,2-TRIARYL-1-BUTENE DERIVATIVES FROM THE FORMULA (R1, R2, R3 AND R4 HAVING THE VALUES INDICATED IN THE DESCRIPTION) OR THEIR PHARMACOLOGICALLY ACCEPTABLE SALTS. THE METHOD CONSISTS OF PHOSPHORYLATING A DERIVATIVE OF 1,1,2-TRIARYL-1-BUTENE AND, IF ANY, REACTING THE RESULTING PRODUCT WITH AN ACID OR A BASE TO FORM ONE OF ITS PHARMACOLOGICALLY ACCEPTABLE SALTS. THE DERIVATIVES OBTAINED ARE APPLIED TO THE TREATMENT OF BREAST CANCER AND ANOVULATORY INFERTILITY. |