http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4103216-A1

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filingDate 2020-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b61ac61293c736c6442904ddbe41fc2
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publicationDate 2022-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-4103216-A1
titleOfInvention Treatment of pain by targeting nr4a1
abstract The present invention involves a method of treating pain. The method treats a patient having post-operative pain or chemotherapy induced neuropathic pain, and it involves a) assessing the patient to determine if they are experiencing post-operative pain or chemotherapy induced neuropathic pain, and if such pain is diagnosed; b) administering to the patient a therapeutically effective amount of an agonist for the nuclear receptor subfamily 4, group A, member 1 (NR4A1). In one embodiment, the agonist is selected from the group consisting of Cytosporone B, Ethyl 2-[2,3,4-trimethoxy-6-(1-octanoyl)-phenyl] acetate (TMPA), 1,3,7-trihydroxy-2,4-diprenylxanthone (CCE9), 1-(3,4,5-trihydroxyphenyl)-nonan-1-one (THPN), DIM-C-pPhOCH3 (C-DIM-5), 1,1-bis(3 '-indolyl)-1-(phenyl)methane (DIM-C-Ph) and 1,1-bis(3 '-indolyl)-1-(p-anisyl)methane (DIM-C-pPhOCH3).
priorityDate 2019-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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