http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4100384-A1

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filingDate 2021-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51f750f402e89217068ae9040877b49f
publicationDate 2022-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-4100384-A1
titleOfInvention Simple manufacturing and purification technology for high purity propofol
abstract A process for manufacturing Pure Propofol with a purity of more than 99.90% is disclosed, said process comprising dissolving Crude Propofol in a solvent in which it is soluble to form a solution, treating the solution with aqueous alkali to form an aqueous alkali layer and a solvent layer, separating the aqueous alkali layer from the solvent layer using a phase separation technique, distilling off the solvent from the solvent layer, and distilling a residue of the solvent containing Propofol using steam or boiling water in a presence of dilute alkali and antioxidant like metabisulfite, under normal pressure or mild vacuum.
priorityDate 2020-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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