| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0655a100cb787468e12b662dbce5b56 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6863 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2021-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74847c793c7136d4fdd586e08b51c126
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e93609e1a8ce6563b05221da09587899
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_889425bdde406dc3197fd2d8b45db925
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e78018daed5160ff52581bedaea45a84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c763d780fa9ea6e823755b5689e09432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1a318df4198e5996a0f0ecb9b4f58ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27bdeaa1c4af8fec0dadaef786c9c501
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ada388b08c010d5a1bcf9c7a500f0657 |
| publicationDate |
2022-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-4097473-A1 |
| titleOfInvention |
Methods for assigning a phenotypic signature for diagnostic and therapeutic applications |
| abstract |
The present invention relates to methods for assigning a phenotypic signature of cells in a liquid biological sample obtained from a mammal, to an innate immune response group using multivariate classification algorithms. Furthermore, the present invention relates to a method for identifying whether a mammal suffers from an inflammation-related disease or is at risk of suffering from an inflammation-related disease using the phenotypic signature. Moreover, the present invention relates to a method for stratifying a mammal suffering from an inflammation-related disease for a treatment against said inflammation-related disease. In addition, the present invention relates to a method for monitoring the progression of an inflammation-related disease in a mammal during a treatment of said mammal. Also, the present invention relates to a method for identifying a compound and/or environmental condition that induces or represses the innate immune response of cells obtained from a mammal. Furthermore, the present invention relates to a use of said phenotypic signature for diagnostic and/or drug de-risking applications. |
| priorityDate |
2020-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |